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Clinical Reports & Studies

​At JBP, we uphold quality built on decades of scientific research and clinical evidence.

Placental extract has been widely studied for use in pharmaceuticals, cosmetics, health supplements, and pet nutrition.
Below are selected studies demonstrating its proven efficacy and safety.

A. Pharmaceuticals

1

Biological effects of human placental extracts -

variations in manufacturing methods and compositions

2

Efficacy and Safety of Placental Extract on Menopausal Symptoms: A Systematic Review

3

Revitalizing liver health: Human placental extract shows promise in chronic liver disease management

  • Journal of Publication： World J Clin Cases. 

  • Publication Date：2025 Oct. 26

  • Authors：Yang Liu, et al

  • Product Category：Pharmaceutical

  • Link：https://pubmed.ncbi.nlm.nih.gov/41113079/

4

Human placental extract improves liver cirrhosis in mice with regulation of macrophages and senescent cells

5

Human placental extract rescues hippocampal damage associated with cognitive impairment in diabetic male rats through antioxidative, anti-inflammatory, and neuromodulatory activities

6

Exosomes derived from human placental mesenchymal stem cells in combination with hyperbaric oxygen therapy enhance neuroregeneration in a rat model of sciatic nerve crush injury

  • Journal of Publication：Regen Ther. 

  • Publication Date：2024 Nov.

  • Authors：Fereshteh Talebpour Amiri, et al

  • Product Category：Pharmaceutical

  • Link：https://pubmed.ncbi.nlm.nih.gov/39687331/

7

Human Placenta Extract (HPH) Suppresses Inflammatory Responses in TNF-α/IFN-γ-Stimulated HaCaT Cells and a DNCB Atopic Dermatitis (AD)-Like Mouse Model

  • Journal of Publication：J Microbiol Biotechnol. 

  • Publication Date：2024 Oct.

  • Authors：Jung Ok Lee, et al

  • Product Category：Pharmaceutical

  • Link：https://pubmed.ncbi.nlm.nih.gov/39252632/

8

Effectiveness and safety of hominis placental pharmacopuncture for chronic temporomandibular disorder: A multi-center randomized controlled trial

9

A farewell to phlebotomy-use of placenta-derived drugs Laennec and Porcine for improving hereditary hemochromatosis without phlebotomy: a case report

10

Placental extract ameliorates liver fibrosis in a methionine- and choline-deficient diet-induced mouse model of non-alcoholic steatohepatitis

11

Placental extract suppresses cardiac hypertrophy and fibrosis in an angiotensin II-induced cachexia model in mice

12

Development of a mouse iron overload-induced liver injury model and evaluation of the beneficial effects of placenta extract on iron metabolism

B. Cosmetics＆Supplements

1

Combined ophthalmic therapy and equine placental extract supplementation to treat corneal perforation in geriatric cats: A case report in the absence of surgical intervention

2

Placental Extract Inhibits Melanogenesis by Inducing the Proteasome-Dependent Degradation of Tyrosinase and TRP-1

3

Supplementation with porcine placenta extract reduces negative emotions and enhances positive emotions in healthy adults: a randomized, double-blind, placebo-controlled study

4

The equine placental extract ameliorates renal damage in mice with adenine-induced chronic kidney disease by inhibiting indoxyl sulfate production

5

Porcine Placental Extract Improves the Lipid Profile and Body Weight in a Post-Menopausal Rat Model Without Affecting Reproductive Tissues

6

Early Effects of Porcine Placental Extracts and Stem Cell-Derived Exosomes on Aging Stress in Skin Cells

7

Supplementation of equine placenta extract on corneal wound in two dogs: Case report

  • Journal of Publication：Open Vet J.

  • Publication Date：2024 Jun.

  • Authors：Tadashi Nakagaki, et al

  • Product Category：Supplements for Pets

  • Link：https://pubmed.ncbi.nlm.nih.gov/39055764/

8

Evaluating the Impact of a Cream Containing Horse Placental Extract on Eye Corner Wrinkles in Healthy Women: Single-Blind Comparative Study

9

Supplementation of equine placenta extract on corneal wound in two dogs: Case report

  • Journal of Publication：Open Vet J. 

  • Publication Date：2024 Jun.

  • Authors：Tadashi Nakagaki, et al

  • Product Category：Health Supplement for Pets

  • Link：https://pubmed.ncbi.nlm.nih.gov/39055764/

10

Successful treatment of ascites accumulation and diarrhea associated with protein-losing enteropathy with oral equine placenta extract supplementation in a dog: A case report

  • Journal of Publication：Open Vet J. 

  • Publication Date：2022 Sep-Oct

  • Authors：Naoki Fukushima, et al

  • Product Category：Health Supplement for Pets

  • Link：https://pubmed.ncbi.nlm.nih.gov/36589412/

11

Equine placental extract supplement as a night barking remedy in dogs with cognitive dysfunction syndrome

  • Journal of Publication：Vet Med Sci. 

  • Publication Date：2022 Sep.

  • Authors：Tatsuya Amano, et al

  • Product Category：Health Supplement for Pets

  • Link：https://pubmed.ncbi.nlm.nih.gov/35921448/

12

Placental extract improves hippocampal neuronal loss and fear memory impairment resulting from chronic restraint stress in ovariectomized mice

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